Compact Discs(CDs) have proven to be versatile for modern chemical research. The recordable CD technology has been utilized to fabricate bio-CDs storing both numeric and genomic information (BioTechniques 2002 33, 435-439). Ligands are also 'burnt' on CDs to selectively bind proteins (Org. Biomol. Chem. 2003, 1, 3244-3249. DOI: 10.1039/b306391g). Besides utilization of the traditional CD technology, treating CD as a plastics surface and the subsequent nanofabrication is also interesting, e.g. SAMs (Anal. Chem. 2001, 73, 4743-4747. DOI: 10.1021/ac015521z) and oxide thin film (Anal. Chem. 2002, 74, 5742-5747. DOI: 10.1021/ac025686n) deposited on CD surface, and CDtrodes (electrodes prepared from CD-Rs, Anal. Chem. 2000, 72, 5503-5506. DOI: 10.1021/ac000437p). A mini-review written by the pioneer of this field, Hua-Zhong Yu, is available in Chem. Commun. 2004, 2633-2636. DOI: 10.1039/b412784f.
These days Andrew and his roommate, a part-time AFM manager, are considering possible cooperation between their fields, cyclodextrin and AFM. Cyclodextrin has successfully self-assembled into monolayers (Self-Assembled Monolayers, SAMs), the so-called 'molecular printboard' (Chem. Eur. J. 2000, 6, 1176-1183) and been subjected to multiple supramolecular interaction, by David N. Reinhoudt and co-workers. But if SAMs can formed on plastics with the current high-speed laser recording technology it would be more exciting. My new colleague, the ferrocene T-Shirt suggests the β-cyclodextrin SAM/ferrocene pair on CD surface in the hope of some redox sensitive properties. Quite fun, isn't it?
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